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In many cases, chloramphenicol is preferred over other antibiotics, as it has the ability to pass deeply through cell membranes and other purulent material to attack bacteria residing in places other antibiotics cannot reach.

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The most serious adverse effect associated with chloramphenicol treatment is bone marrow toxicity, which may occur in two distinct forms bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and aplastic anemia, which is idiosyncratic rare, unpredictable, and unrelated to dose and generally fatal.

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Therapy consists of topical antibiotics administered in the form of eye drops, applied in the lower conjunctival sac, and chloramphenicol eye drops have been found to be quite effective sinclair leigh 1988; h rven 1993 .

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Chloramphenicol prevents bacteria making an essential nutrient required for growth and multiplication.

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precautions before using chloramphenicol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.

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