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In another study of patients taking proscar alone or in combination with doxazosin another 5-alpha-reductase inhibitor , four out of 1,554 patients developed breast cancer.

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for children the safety and effectiveness of doxazosin haven t been established in people younger than 18 years old for treating benign prostatic hyperplasia bph .

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the low plasma concentrations of known active and inactive metabolites of doxazosin 2-piperazinyl, 6 -and 7 -hydroxy and 6-and 7-o-desmethyl compounds compared to parent drug indicate that the contribution of even the most potent compound 6 -hydroxy to the antihypertensive effect of doxazosin in man is probably small.

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doxazosin is contraindicated as monotherapy in patients with either overflow bladder or anuria with or without progressive renal insufficiency.

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