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Continuation of metformin reduces early pregnancy loss in obese pakistani women with polycystic ovarian syndrome.

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in a two-day study in healthy subjects, sitagliptin alone increased active glp-1 concentrations, whereas metformin alone increased active and total glp-1 concentrations to similar extents.

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we therefore analyzed the effect of metformin on the expression of these factors.

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akt inhibition, known to correlate with impaired cell survival, was recently shown to represent a molecular correlate of metformin direct antitumoral effects 15 .

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