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cases of myopathy, including rhabdomyolysis, have been reported with simvastatin coadministered with colchicine, and caution should be exercised when prescribing simvastatin with colchicine.

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combining colchicine with statins, for example atorvastatin lipitorsimvastatin zocorand lovastatin mevacorlopid gemfibrozilor fenofibrate increases the risk of muscle related adverse effects because these drugs also cause muscle related side effects.

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